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Ketamine-Assisted Mindfulness for Lasting Change

For those navigating anxiety, depression, or unhelpful behavioral patterns, this 12-week program offers a supportive way to soften the grip of survival habits and build new pathways rooted in clarity, commitment, and self-compassion.

Calm Mind Open Heart Ketamine-Assisted Mindfulness

Calm Mind Open Heart Ketamine-Assisted Mindfulness (CMOH-KAM) is a 12-week, mindfulness-based program that weaves together low-dose ketamine, meditation, breathwork, and support to help mindfulness become something you actually live, not just something you practice on the cushion. It’s for people who are tired of cycling through programs and quick fixes, and who are ready for meaningful, steady change grounded in awareness, focus, compassion, and the ability to pause and choose their path.

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While ketamine is included in this program, it isn’t the driver of transformation. Instead, it serves as a temporary support to soften old patterns and open space for the creation of new ones that align with who you’re becoming. Research suggests that ketamine may increase neuroplasticity of the brain, much like adding “Miracle-Gro” to the soil. But as any gardener knows, growing the garden you want needs care and intention. Throw down a bunch of Miracle-Gro and walk away, you might return to find a beautiful garden or you might return to find a bunch of weeds. This program encourages your not to walk away and hope that something wonderful will grow. Instead, you learn how to use mindfulness skills as the tools to gently cultivate what’s meaningful, while clearing what no longer serves you.

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What Makes This Program Unique

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Most ketamine-assisted psychotherapy (KAP) approaches use a traditional talk-therapy model in which the ketamine experience is explored through interpretation, emotional processing, and meaning-making—often drawing from psychodynamic or psychoanalytic frameworks that focus on uncovering unconscious material.

CMOH-KAM takes a different approach by centering skill-building rather than analysis, using ketamine as a temporary support to soften rigid patterns and make it easier to practice the mindful habits that lead to sustainable, values-aligned change. The program focuses on developing four core mindfulness-based skills:

 

  • Awareness: noticing neruocognitive patterns and enhancing perception of your body and environment

  • Focus: sustaining attention on what matters to you

  • Inhibition: pausing before acting, interrupting automatic patterns

  • Compassion: responding with acceptance, rather than judgment or self-criticism
     

Together, these skills help reshape long-held cognitive, emotional, and behavioral patterns that may have served a purpose in the past but no longer support your wellbeing. Over time, these mindfulness-based skills become reliable inner resources that allow you to move through life with greater clarity, calm, and an open heart.

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What the Program Involves

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Over 12 weeks, you’ll move through a gentle, structured process designed to meet you exactly where you are. No prior experience with meditation or breathwork is required—everyone begins from a different place, and the program is built to support beginners and seasoned practitioners alike. A companion workbook guides you step-by-step, helping you turn the core mindfulness skills into daily habits that feel natural and embodied over time.​

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Throughout the program, you will engage in:

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  • Daily meditation and guided pranayama practices

  • A gentle, step-by-step plan and companion workbook for building mindful habits that fit into your daily life

  • Six low-dose ketamine-assisted meditation sessions (ketamine use is optional)

  • Weekly therapeutic progress sessions to navigate barriers and support steady growth
     

The pace is intentionally slow, steady, and supportive—focused on helping you make meaningful, sustainable, mindfulness-based changes that endure well beyond the 12 weeks.

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Who This Program Is For

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This program may be a good fit if:

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  • You’re experiencing depression — especially if you’ve tried multiple treatments and still feel stuck (often referred to as treatment-resistant depression). You may notice low mood, self-criticism, loss of interest, or a sense of heaviness that feels hard to shift.
     

  • You're experiencing anxiety — where worry feels constant, your mind has trouble settling, or your body stays on alert even when nothing is “wrong”. Maybe you've tried other forms of treatment, but your nervous system keeps pulling you into tension, looping thoughts, or overwhelm.

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Ketamine is Optional, Not Required
 

The use of ketamine is optional, not required. The heart of CMOH-KAM is the cultivation of mindfulness-based skills—awareness, focus, inhibition, and compassion—supported by daily meditation and pranayama (breathwork) practice. Ketamine is offered as an optional support because research suggests it may temporarily enhance neuroplasticity and help you perceive thoughts and sensations with greater openness, making habitual patterns easier to recognize and shift. The ketamine enhances, but it is the practice that creates the change.

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(651) 400-9435 | ext 105

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Research

As with any powerful therapeutic tool, ketamine-assisted work carries both potential benefits and real risks. That’s why it’s essential that this program is grounded in the emerging research on ketamine-assisted psychotherapy and mindfulness, not just what “feels right” or being overly focused on the evidence where it seems promising.

 

Evidence-informed care helps to point to developing processes that are thoughtful and aligned with what we currently understand about how change happens. At the same time, it’s important to acknowledge that this form of ketamine-assisted therapy—like all emerging psychedelic approaches—does not offer guaranteed outcomes, and each person’s response is unique. Below you’ll find links to the studies that have shaped and guided the development of this program.

Anxiety 

Fumero, A., Peñate, W., Oyanadel, C., & Porter, B. (2020). The Effectiveness of Mindfulness-Based Interventions on Anxiety Disorders. A Systematic Meta-Review. European Journal of Investigation in Health, Psychology and Education, 10(3), 704–719. https://doi.org/10.3390/ejihpe10030052 (PubMed

Glue, P., et al. (2017). Ketamine’s dose-related effects on anxiety symptoms in patients with severe generalized anxiety disorder or social anxiety disorder: a double-blind, randomized, placebo-controlled trial. Journal of Psychopharmacology, 31(10), 1302–1310. (PubMed)

Hoge, E. A., Bui, E., Mete, M., Dutton, M. A., Baker, A. W., & Simon, N. M. (2023). Mindfulness-Based Stress Reduction vs Escitalopram for the Treatment of Adults With Anxiety Disorders: A Randomized Clinical Trial. JAMA Psychiatry (Chicago, Ill.), 80(1), 13–21. https://doi.org/10.1001/jamapsychiatry.2022.3679 (JAMA Psychiatry)

Mills, N. T., Nikolin, S., Glozier, N., Barton, D., Baune, B. T., Fitzgerald, P. B., Glue, P., Sarma, S., Rodgers, A., Hadzi-Pavlovic, D., Alonzo, A., Dong, V., Martin, D., Mitchell, P. B., Berk, M., Carter, G., Hackett, M. L., Somogyi, A. A., Mihalopoulos, C., Loo, C. K. (2025). Effect of ketamine on anxiety: findings from the Ketamine for Adult Depression Study. British Journal of Psychiatry, 227(3), 601–607. https://doi.org/10.1192/bjp.2024.250 (BJPsych)

Depression

Alkan, E., Kumar, G., Ravichandran, S., Kaushal, S. R., Salazar-de-Pablo, G., Alerci, L., Michaud-Feinberg, J., Gutiérrez-Rojas, L., Zorzi, C., Klauser, P., Golay, P., Kramer, U., & Alameda, L. (2025). Effectiveness of mindfulness based interventions in reducing depressive symptoms across mental disorders: A meta-analysis of randomized controlled trials. Psychiatry Research, 348, Article 116473. https://doi.org/10.1016/j.psychres.2025.116473 (PubMed)

Arabzadeh, S., Hakkikazazi, E., Shahmansouri, N., Tafakhori, A., Ghajar, A., Jafarinia, M., & Akhondzadeh, S. (2018). Does oral administration of ketamine accelerate response to treatment in major depressive disorder? Results of a double-blind controlled trial. Journal of Affective Disorders, 235, 236–241. https://doi.org/10.1016/j.jad.2018.02.056 (PubMed)

Rosenblat, J. D., Carvalho, A. F., Li, M., Lee, Y., Subramanieapillai, M., & McIntyre, R. S. (2019). Oral Ketamine for Depression: A Systematic Review. The Journal of Clinical Psychiatry, 80(3). https://doi.org/10.4088/JCP.18r12475 (PubMed)

Veraart, J. K. E., Smith-Apeldoorn, S. Y., Kamphuis, J., Spijker, J., van der Meij, A., van Asselt, A. D. I., aan het Rot, M., & Schoevers, R. A. (2024). Oral esketamine in patients with treatment-resistant depression: a double-blind, randomized, placebo-controlled trial with open-label extension. Molecular Psychiatry, 29(9), 2657–2665. https://doi.org/10.1038/s41380-024-02478-9 (PubMed)

Risk & Safety

Sayad, R., Elsaeidy, A. S., Anis, A. M., Atef, M., Hawash, E. A., Saad, H. A., Hamad, K. A. A., & Kohaf, N. A. (2025). Safety considerations and risk mitigation strategies for ketamine use: a comprehensive review. Annals of Medicine and Surgery, 87(5), 2829–2837. https://doi.org/10.1097/MS9.0000000000003232 (PubMed)

Please Note: If you are contemplating suicide or are experiencing a medical or mental health emergency, please call or text the Suicide & Crisis Lifeline 9-8-8.

 

Information provided on this website DOES NOT create a therapist--client relationship between you and Cliff Dahlberg. Please note that requesting an appointment does not guarantee you will receive mental health services.

© 2025 Cliff Dahlberg 

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